the comparison of staphylococcus aureus isolated from blood and wound specimens for genes encoding polysaccharide intercellular adhesion (pia)

conclusions these findings showed no significant difference regarding the presence of icaadbc genes between blood and wound isolates. background the polysaccharide intercellular adhesion (pia) produced by staphylococcus aureus is effective in the protection of isolates from outer harsh conditions and progress of infection. objectives the aim of this study was to compare the icaabcd genes encoding polysaccharide intercellular adhesion (pia) between blood and wound isolates of staphylococcus aureus (s. aureus) in tehran. patients and methods forty-eight clinical isolates (including 30 blood and 18 skin wounds) were collected from patients and were identified. next, meca gene, sccmec types and icaabcd genes were detected among blood and wound isolates of s. aureus by pcr assay and specific primers. results nine (19%) out of 12 methicillin resistant s. aureus (mrsa) isolates harbored sccmec type iii and three (6.2%) isolates harbored sccmec type v. prevalence of icaa, icab, icac and icad in blood isolates was twenty-one (70%), fourteen (48%), nineteen (64%) and eighteen (60%), respectively; while the prevalence in wound isolates was as nine (50%), seven (39%), six (34%) and twelve (67%), respectively.